主题：PET/CT在恶性肿瘤中的应用 -- 良金百辟
家园 随便一例 http://www.medpagetoday.com/Surgery/Otolaryngology/17053
By Charles Bankhead, Staff Writer, MedPage Today
Published: November 17, 2009
Reviewed by Zalman S. Agus, MD; Emeritus Professor
University of Pennsylvania School of Medicine and
Dorothy Caputo, MA, RN, BC-ADM, CDE, Nurse Planner
For assessment of tumor response at the primary site, PET-CT had a negative predictive value of 92%. However, false-positive results were common, reflected in a specificity of 54%.
54%是极低的Specificity。如果是50%的话就等于扔硬币了。
- 复 随便一例
家园 只有在肿瘤病人人群中PET-CT的特异度才足够高 比如
Journal of Nuclear Medicine Vol. 47 No. 8 1255-1259
All patients underwent successful surgery, and pathologic examination confirmed nodes positive for metastasis in 32 patients and 82 of 397 excised nodal groups.
The sensitivity, specificity, accuracy, positive predictive value, and negative predictive value of PET/CT were 93.90% (77/82 nodal groups), 92.06% (290/315), 92.44% (367/397), 75.49% (77/102), and 98.31% (290/295), respectively
这也就是为什么你会看到很多文献说PET-CT特异性高的原因--不同的人群。
家园 特异性的定义 是指在阴性者中正确诊断阴性的能力
请问您能给出PET-CT的特异性指标及其来源么？特别是号称其特异性很高的数据，请您仔细地看是在哪个人群里做的。不妨将您看到的这些证据贴上来，我们一起看好了。