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主题:关于牛黄解毒片求教 -- 燕人

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家园 我最喜欢可以证伪的辩论

你们两位,一个说是泻药,另一个说导致便秘,于是我去查了一下。

百度上,两种说法都有,其中有医生解释说便秘是糖尿病本身就会减少肠蠕动导致的,不是概要导致的。

于是我去查国外的网站,https://www.mayoclinic.org/drugs-supplements/metformin-oral-route/side-effects/DRG-20067074

上面说的常见副作用有一个是腹泻,另一个不常见的作用是大便不正常,怎么个不正常就没有说。

然后我又查了一下,这里有个数字:https://www.ehealthme.com/ds/metformin/constipation/

345,599 people reported to have side effects when taking Metformin.

Among them, 5,445 people (1.58%) have Constipation.

确实有1.58%的病人发生便秘。

这里又有一篇文章,说了为何会导致腹泻:https://www.25doctors.com/metformin-diarrhea

Even though there are a number of proposed hypotheses, the exact manner in which metformin causes gastrointestinal problems is not very certain. On one hand, it is believed that gastrointestinal problems likely result from the concentration of metformin in the intestine after been taken by mouth.

On the other hand, it is believed that metformin structurally can fit into a certain receptor in the body called 5-HT3. When the 5-HT3 receptor is activated, effects like nausea, vomiting and diarrhea result.

答案是原因未明,相信是一个叫 5-HT3受体导致的。

调查结果总体来说,陈王说的这种药会导致腹泻是对的,真理说的导致便秘也是可能的,只是概率较低。

但是,我强烈反对乱吃药,尤其是这种控制血糖的药,这种药应该在专业医生的指导下服用才对。

通宝推:燕人,
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