主题:【讨论】我支持转基因研究但选择不吃转基因作物 -- snark
你引用的草甘膦毒性的各种数据,来源于哪篇论文,论文作者是谁,发表在哪里?发表时间是什么时候这四个都没有,你说那是不是三无数据呢?
我还是给你看一看四有论文的数据吧
论文名称:Glyphosate-based herbicides are toxic and endocrine disruptors in human cell lines(草甘膦对人体细胞的内分泌干扰)
论文作者:
Céline Gasniera, Coralie Dumontb, Nora Benachoura, Emilie Claira, Marie-Christine Chagnonb, Gilles-Eric Séralinia,
论文发表于
Toxicology
Volume 262, Issue 3, 21 August 2009, Pages 184–191
发表时间是2009年8月
论文摘要:
Glyphosate-based herbicides are the most widely used across the world; they are commercialized in different formulations. Their residues are frequent pollutants in the environment. In addition, these herbicides are spread on most eaten transgenic plants, modified to tolerate high levels of these compounds in their cells. Up to 400 ppm of their residues are accepted in some feed. We exposed human liver HepG2 cells, a well-known model to study xenobiotic toxicity, to four different formulations and to glyphosate, which is usually tested alone in chronic in vivo regulatory studies. We measured cytotoxicity with three assays (Alamar Blue, MTT, ToxiLight), plus genotoxicity (comet assay), anti-estrogenic (on ERα, ERβ) and anti-androgenic effects (on AR) using gene reporter tests. We also checked androgen to estrogen conversion by aromatase activity and mRNA. All parameters were disrupted at sub-agricultural doses with all formulations within 24 h. These effects were more dependent on the formulation than on the glyphosate concentration. First, we observed a human cell endocrine disruption from 0.5 ppm on the androgen receptor in MDA-MB453-kb2 cells for the most active formulation (R400), then from 2 ppm the transcriptional activities on both estrogen receptors were also inhibited on HepG2. Aromatase transcription and activity were disrupted from 10 ppm. Cytotoxic effects started at 10 ppm with Alamar Blue assay (the most sensitive), and DNA damages at 5 ppm. A real cell impact of glyphosate-based herbicides residues in food, feed or in the environment has thus to be considered, and their classifications as carcinogens/mutagens/reprotoxics is discussed.
我们发现在0.5ppm的浓度就已经对人体的内分泌产生了干扰,在5ppm的情况下发生了DNA的损伤,其他很多专业名词你自己看看吧
至于什么草甘膦毒性比食盐还低的话,这不是耍流氓又是什么?
没有人把盐巴一把抓起来吃,大家都是把食盐溶在水里面吃,而溶在水里面吃的食盐的毒性与干吃盐巴的毒性等同吗(就算食盐含量等同)?后者对生物的影响主要是因为食盐浓度太高,而细胞内食盐浓度低,形成一个压力,即所谓的渗透压,这样大的浓度差足以把细胞给压破掉,而用水一溶,这个渗透压就急剧减小,到生理盐水的浓度的时候这个渗透压等于0,这篇文章的作者把草甘膦的毒性和本应该溶在水里的食盐的干吃的毒性相比,这是什么意思?这真的是专业不够还是在耍流氓呢?
- 相关回复 上下关系8
🙂你不如说老百姓的感受都是没有意义的罢了 思想的行者 字100 2014-10-07 23:06:47
🙂你现在努力也不晚 1 雨落幽燕x 字88 2014-10-07 23:19:36
🙂你不怕所谓的科普书忽悠你? 思想的行者 字127 2014-10-08 00:01:33
🙂你还是想清楚再引用四无论文的数据好不好?
🙂这篇回复不是给罗教主看的 1 雨落幽燕x 字122 2014-10-01 21:06:17
🙂塞拉利尼的的转基因玉米试验和张启发的华恢一号试验相互验证 1 思想的行者 字208 2014-10-01 22:01:06
🙂习近平谈自己对转基因问题的看法 7 苏迅 字690 2014-09-28 02:27:00
🙂这个帖子争论的焦点就是慎重 snark 字724 2014-09-29 23:58:32