- == 系统问题,暂停聊天功能。==
- 【征集】西西河的经济学,及清流措施,需要主动参与者,『稷下学宫』新认证方式,24年网站打算和努力目标
主题:【原创】关于央视新闻《果子狸含冤10年》的求实 -- 善良的恶霸地主
共:💬9 🌺32 新:
发文之后,收到@京虎子的回复:
不是你说的这么回事。当年大家只是认为蝙蝠也是载体之一,那两篇文章都没有下定论。最近发现另外一种冠状病毒从蝙蝠传染到人,才旧事重提,也间接地证明了果子狸可能不是原始宿主。所以才去采访袁。这件事前一阵听袁的同事提起过。
于是我把原文删了,以免以讹传讹。
刚才又去看了看那两篇论文的摘要,虽然我不是学这个的,但从两篇论文的摘要看,应该不仅仅是“认为蝙蝠也是载体之一”,而都是在和果子狸比较,认为蝙蝠更像是原始宿主。难道我理解错了吗?附上两篇的摘要:
Severe acute respiratory syndrome (SARS) emerged in 2002 to 2003 in southern China. The origin of its etiological agent, the SARS coronavirus (SARS-CoV), remains elusive. Here we report that species of bats are a natural host of coronaviruses closely related to those responsible for the SARS outbreak. These viruses, termed SARS-like coronaviruses (SL-CoVs), display greater genetic variation than SARS-CoV isolated from humans or from civets. The human and civet isolates of SARS-CoV nestle phylogenetically within the spectrum of SL-CoVs, indicating that the virus responsible for the SARS outbreak was a member of this coronavirus group.
Although the finding of severe acute respiratory syndrome coronavirus (SARS-CoV) in caged palm civets from live animal markets in China has provided evidence for interspecies transmission in the genesis of the SARS epidemic, subsequent studies suggested that the civet may have served only as an amplification host for SARS-CoV. In a surveillance study for CoV in noncaged animals from the wild areas of the Hong Kong Special Administration Region, we identified a CoV closely related to SARS-CoV (bat-SARS-CoV) from 23 (39%) of 59 anal swabs of wild Chinese horseshoe bats (Rhinolophus sinicus) by using RT-PCR. Sequencing and analysis of three bat-SARS-CoV genomes from samples collected at different dates showed that bat-SARS-CoV is closely related to SARS-CoV from humans and civets. Phylogenetic analysis showed that bat-SARS-CoV formed a distinct cluster with SARS-CoV as group 2b CoV, distantly related to known group 2 CoV. Most differences between the bat-SARS-CoV and SARS-CoV genomes were observed in the spike genes, ORF 3 and ORF 8, which are the regions where most variations also were observed between human and civet SARS-CoV genomes. In addition, the presence of a 29-bp insertion in ORF 8 of bat-SARS-CoV genome, not in most human SARS-CoV genomes, suggests that it has a common ancestor with civet SARS-CoV. Antibody against recombinant bat-SARS-CoV nucleocapsid protein was detected in 84% of Chinese horseshoe bats by using an enzyme immunoassay. Neutralizing antibody to human SARS-CoV also was detected in bats with lower viral loads. Precautions should be exercised in the handling of these animals.
- 相关回复 上下关系5
😄这是要害果子狸啊,好容易吓得人不敢下口了 bjinjin 字0 2013-04-01 06:45:37
🙂很有道理啊。 xiaobailong 字0 2013-04-01 06:12:46
🙂央视这报道还有更多错误的地方 1 xiaobailong 字169 2013-03-31 14:55:11
😭我删贴又改回的原因
🙂赞认真精神 xiaobailong 字0 2013-04-01 06:12:18