主题：【标杆篇】方舟子 何许人也 -- 老顽童

证据6

　　证据名称：肖传国2000年获Pfizer泌尿外科学者奖证书。

　　证据来源：美国泌尿外科学会。

　　证明内容：肖传国2000年获Pfizer泌尿外科学者奖。

　　证明目的：肖传国获美国泌尿外科学会Pfizer泌尿外科学者奖。

　　

本院认为：原告的“肖氏反射弧”理论，在国际上有获奖证书，国内有鉴定结论和获奖证书，国内教科书亦曾引用其理论，原告的“肖氏反射弧”理论是客观存在的。被告方是民在网上搜索不到“肖氏反射弧”，不等于“肖氏反射弧”不存在。被告方是民认为“肖氏反射弧”在国际上毫无影响、国内专家没有得到认同的评论不能成立。

Because from earlier experiments in rats and a pilot study in humans a no effect level of glycyrrhizic acid could not be established, a second experiment was performed in healthy volunteers. The experiment was performed in females only, because the effects were most marked in females in the pilot study. Doses of 0, 1, 2 and 4 mg glycyrrhizic acid/kg body weight were administered orally for 8 weeks to 39 healthy female volunteers aged 19-40 years.

The experimentlasted 12 weeks including an adaptation and a “wash-out” period.Ano-effectlevel of2 mg/kgis proposed from the results ofthis study, from which an acceptable daily intake (ADI) of 0.2 mg/kg body weight can be extrapolated with a safety factor of 10. This means consumption of 12 mg glycyrrhizic acid/day for a person with a body weight of 60 kg. This would be equal to 6 g licorice a day, assuming that licorice contains 0.2% of glycyrrhizic acid.

The proposed ADI is below the limit advised by the Dutch Nutrition Council of 200 mg glycyrrhizic acid/day. This reflects the relatively mild acute toxicity of glycyrrhizic acid, which is also emphasised by the “generally recognised as safe” (GRAS) status of glycyrrhizic acid in the USA in 1983. However, the long-term effects of a mild chronic intoxication (causing, for example, a mild hypertension), although not immediately lethal, justify special attention to the amount of glycyrrhizic acid used daily.