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主题:【原创】今天杯具了,今天药物中毒了 -- 企鹅

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家园 呵呵,是药三分毒

更何况您这药也可以做兽药,能没反应吗?

教训哈

Adverse effects

Meloxicam use can result in gastrointestinal toxicity and bleeding, tinnitus, blinding headaches, rash, very dark or black stool (sign of intestinal bleeding). It has fewer gastrointestinal side effects than diclofenac,[4] piroxicam,[5] naproxen,[6] and perhaps all other NSAIDs which are not COX-2 selective.[4] Although meloxicam does inhibit thromboxane A, it does not appear to do so at levels that would interfere with platelet function.

Veterinary use

Under the brand name Metacam, meloxicam is also used in the veterinary field, most commonly in dogs, but also sees off-label use in other animals such as cattle, cats and exotics, [7][8] however the U.S. Food and Drug Administration sent a Notice of Violation to the manufacturer for its promotional materials which included promotion of the drug for off-label use.[9] In the U.S. the drug is indicated for management of pain and inflammation associated with osteoarthritis in dogs only. In Europe, where the product has been available since the early 1990s, it is also prescribed and licensed for other anti-inflammatory benefits including relief from both acute and chronic pain in dogs. Side effects in animals are similar to those found in humans; the principal side effect is gastrointestinal irritation (vomiting, diarrhea and ulceration). Rarer but important side effects include liver and kidney toxicity.

Since 2003, the oral (liquid) formulations of Metacam have been licensed for use in dogs only,[10] with the January 2005 product insert specifically warning in bold-face type: "Do not use in cats."[11] An injectable formulation for use in dogs was approved by the FDA November 2003,[12] with a formulation for cats, for surgical use only, approved in October, 2004.[13]

In the U.S., per the manufacturer's clinical instructions as of July 2010, injectable Metacam is indicated in operative use with felines as a single, one-time dose only, with specific and repeated warnings not to administer a second dose.[14] In June 2007, a new oral version of Metacam was licensed in Europe for the long-term relief of pain in cats. As of June 2008, Metacam is registered for long term use in cats in Australia, New Zealand, and throughout Europe.

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