主题:【整理】上海抗疫摆烂的余响——巴黎贝甜事件 -- 乾道学派
https://pubmed.ncbi.nlm.nih.gov/8939440/
Mol Microbiol. 1996 Nov;22(3):583-92. doi: 10.1046/j.1365-2958.1996.00133.x.
Site-directed mutagenesis of the katG gene of Mycobacterium tuberculosis: effects on catalase-peroxidase activities and isoniazid resistance
D A Rouse 1, J A DeVito, Z Li, H Byer, S L Morris
"Rouse et al. validated this hypothesis in a well-designed
study that investigated the impact of specific
missense m
utations on KatG function. This was
accomplished by introducing fourteen genetically
defined mutations at thirteen different codons (36)."
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