主题：【原创】备忘：新冠病毒溯源 -- CHS1

【说明】这是一篇在网上寻得的“道听途说”，来自赵盛烨的微博：https://weibo.com/xodn?nick=%E8%B5%B5%E7%9B%9B%E7%83%A8&is_all=1#_rnd1597370095301。笔者无意辨识它的真假，只是希望把它如实记录下来。感谢西河宝地提供了一个相对宽松的环境，能让笔者志史志异。

【译文】

萨曼莎·希尔（Samantha Hill）

抱歉，我们在新型冠状病毒爆发中扮演了邪恶角色

我匿名发帖。我曾是个美国人，但更多是印度人。我曾在曼尼托巴大学读书，并在德里克堡（Fort Detrick）实验室做过一些杂活。我上司和我几乎完全了解新冠病毒的一切，他也是因此而被杀害的。现在我回到了印度，振作精神，决定说出真相，希望大家了解到真相时我还活着。

我工作的地方相当神秘，是许多军方生物武器和化学武器的研发基地，有最高机密性。像我这样的小角色只能胜任服务客户公司的工作，无法接触到任一实验的全部信息。

我的头号客户是吉利德科学（Gilead Sciences）公司。他们曾在中东传播中东呼吸综合征（MERS），以便避开联邦限制，测试一种新药的药效。他们已经用瑞德西韦进行过各种人体安全性测试了，这是个公开的秘密，但我主要要说的并不是这个。

我的上司是弗兰克·普拉默（Frank Plummer）教授，他曾是拉斐尔·巴里克（Ralph S. Baric）教授最好的朋友。他俩在生物科学领域都取得了巨大成就，这必定是湿婆神的保佑，我们凡夫俗子无法企及。普拉默教授相对更保守，而巴里克教授则是一位科学狂人，经常做一些高风险实验。我到现在才理解，他这么做很可能不是出于自己的意愿，而是被吉利德科学公司要求的。

在我们发现吉利德科学公司研发的编号为GS-5734的药物抗击埃博拉病毒非常有效后，对其进行了多次实验。该化合物很可能是一种广谱抗病毒药物，其作用机理非常特殊，与众不同，因此我们针对一系列单链RNA病毒进行了实验，包括拉沙热病毒（Lassa fever virus）、尼帕病毒（Nipah virus）、亨德拉病毒（Hendra virus）及冠状病毒等。我们在冠状病毒实验中遇到了一些特殊情况，尚不清楚GS-5734能否有效抗击MERS和SARS。为了进一步进行研究，吉利德科学公司的阿德里安·雷（Adrian S. Ray）和理查德·马克曼（Richard L. Mackman）分别委托北卡罗来纳大学疾控中心的美国陆军医学传染病研究所（United States Army Medical Research Institute of Infectious Diseases）进行了不同领域的研究，以下这些在线论文也正是由他们发表的。这些项目的负责人包括希娜·巴维利（Sina Bavari）（小分子GS-5734对恒河猴埃博拉病毒的治疗功效，Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys，Warren et al., 2016）、克里斯蒂娜·斯皮罗普罗（Christina F. Spiropoulou）（GS-5734及其母体核苷类似物对丝状病毒、肺病毒和副黏液病毒的抑制，GS-5734 and its parent nucleoside analog inhibit Filo-, Pneumo-, and Paramyxoviruses，Lo, et al. 2017）、拉斐尔·巴里克等（广谱抗病毒GS-5734对人畜共患的流行冠状病毒的抑制，Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses，Sheahan et al., 2017）。到目前为止，我们实验中使用的所有SARS样本均来自巴里克教授组，因为他是制造SARS的专家，发表过《重症急性呼吸综合征冠状病毒全长感染cDNA的反向遗传学》的论文（Reverse genetics with a full-length infectious cDNA of severe acute respiratory syndrome coronavirus，Yount, et al., 2003），这意味着他从2003年起就可以复制SARS病毒，不受任何限制。他还为中国科学院提供了研究经费，让石正丽扮演了天真的白雪公主——帮助他确定了中国南方变异SARS的基因变异片段。

实际上，自从石正丽在中国发现的SHC014基因片段被巴里克教授采用，并于2015年在德里克堡实验室合成为一种新型病毒——即如今的新型冠状病毒之后，石正丽就已经完成了巴里克教授交给她的任务。

这是一次伟大的实验，在病毒学和生物学上取得了巨大的进步，因为这种RNA的合成是前所未有的。普拉默教授一直反对这一实验，认为它违背了科学道德。但巴里克教授和吉利德科学公司坚持认为这种合成病毒可以在对比实验中作为原始SARS病毒的参考，是GS-5734药物实验必不可少的原料。

据我所知，人工繁殖新型SARS病毒应该是由国防部委托的一项开发生物武器的研发项目。但吉利德科学公司也有自己的秘密计划：一旦病毒泄漏并传播，他们将以极高昂的价格在全球出售GS-5734。

需要说明的是，新冠病毒在全球的肆虐并不是吉利德科学公司或国防部有意采取的行动，而是实验泄漏导致的。2019年5月，我们实验中出现了一次泄漏，但直到疾控中心于2019年7月发现马里兰州的实验室附近有村民受到感染，我们才意识到这次泄漏。我们后来发现实验室的废水处理系统存在严重问题，但为时已晚了。

互联网上流传的推测性事实并不完全准确：当时在南美肆虐的流感并非完全是SARS-II（即新冠病毒），而是两种病毒同时传播造成的。由于疾控中心的干涉，位于各个州的前哨实验室没有进行冠状病毒测试。

由于巴里克教授的建议，我们的实验室、军方和吉利德科学公司都不会承认病毒的来源，而是默认将中国云南省的蝙蝠作为病毒来源。由于中国科学家的实验和论文已经证明了自然界中的基因变异及SARS-I原型起源于中国，这么做是可行的。

新冠病毒的传播中存在一些争议话题。为了确保该病毒不会造成无法收拾的损害，疾控中心在中情局的协助下启动了EVENT201演习。尽管演习结果不尽人意，巴里克教授还是认为，由于ACE2基因在不同种族中的分布不同，SARS-II不会对美国白种人造成巨大伤害。这就是中央情报局最终决定不对病毒传播进行预警的原因。

巴里克教授、吉利德科学公司、黑石公司（BlackRock，吉利德科学公司的投资子公司）和疾控中心是整个事件的决策者。会议的所有成员都是共和党人，他们向美国创新办公室和杰拉德·库什纳（Jared Kushner）汇报。

2019年12月是转折点，当时一名水手受到SARS-II感染后继续工作，碰巧将病毒封装在了海鲜包装中，后者随后经由非法市场运到了中国武汉的海鲜市场。出人意料的是，中国的防疫部门发现了这种病毒，这很可能要归功于他们的SARS预防经验。不然的话，这种病毒性肺炎可能会被当做细菌性肺炎，并被称做一种新型流感，不会引起足够的重视。

中国政府发现SARS-II后，我的上司普拉默教授打算与中国科研机构分享采用GS-5734对抗SARS-II的经验，但他在从肯尼亚飞往中国时被暗杀了。得知这一消息后，我不得不回到印度躲藏起来。

据我所知，一些知道真相的同事在过去的几个月中被杀害了，另一些则消失了。其他所有屈服于巴里克教授的从业者未经他的许可都不敢表达他们的怀疑。一旦提出质疑，他们的职业生涯就将结束，不会再有出版商接受他们的论文。

我不知道我还能在世上活多久，我内心深处感到内疚。我不能让这么多人连真相也不清楚就白白死去，所以我在此将其公之于众，愿湿婆神保佑大家。他们当然会否认所有这一切，甚至会否认我的身份乃至我的存在。他们会尽全力杀害我，所以我就在这里说再见了。大家再见！我很抱歉！

参考文献：

[1] B. Yount, K. M. Curtis, E. A. Fritz, L. E. Hensley, P. B. Jahrling, E. Prentice, M. R. Denison, T. W. Geisbert and R. S. Baric, "Reverse genetics with a full-length infectious cDNA of severe acute respiratory syndrome coronavirus," Proceedings of the National Academy of Sciences of the United States of America, vol. 100, no. 22, pp. 12995-13000, 2003.

[2] T. K. Warren, R. Jordan, M. K. Lo, A. S. Ray, R. L. Mackman, V. Soloveva, D. Siegel, M. Perron, R. Bannister, H. C. Hui, N. Larson, R. Strickley, J. Wells, K. S. Stuthman, S. A. Van Tongeren, N. L. Garza, G. Donnelly, A. C. Shurtleff, C. J. Retterer, D. Gharaibeh, R. Zamani, T. Kenny, B. P. Eaton, E. Grimes, L. S. Welch, L. Gomba, C. L. Wilhelmsen, D. K. Nichols, J. E. Nuss, E. R. Nagle, J. R. Kugelman, G. Palacios, E. Doerffler, S. Neville, E. Carra, M. O. Clarke, L. Zhang, W. Lew, B. Ross, Q. Wang, K. Chun, L. Wolfe, D. Babusis, Y. Park, K. M. Stray, I. Trancheva, J. Y. Feng, O. Barauskas, Y. Xu, P. Wong, M. R. Braun, M. Flint, L. K. McMullan, S.-S. Chen, R. Fearns, S. Swaminathan, D. L. Mayers, C. F. Spiropoulou, W. A. Lee, S. T. Nichol, T. Cihlar and S. Bavari, "Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys," Nature, vol. 531, pp. 381-385, 2016.

[3] M. K. Lo, R. Jordan, A. Arvey, J. Sudhamsu, P. Shrivastava-Ranjan, A. L. Hotard, M. Flint, L. K. McMullan, D. Siegel, M. O. Clarke, R. L. Mackman, H. C. Hui, M. Perron, A. S. Ray, T. Cihlar, S. T. Nichol and C. F. Spiropoulou, "GS-5734 and its parent nucleoside analog inhibit Filo-, Pneumo-, and Paramyxoviruses," Sci Rep., vol. 7, p. 43395, 2017.

[4] T. P. Sheahan, A. C. Sims, R. L. Graham, V. D. Menachery, L. E. Gralinski, J. B. Case, S. R. Leist, k. Pyrc, J. Y. Feng, I. Trantcheva, R. Bannister, Y. Park, D. Babusis, M. O. Clarke, R. L. Mackman, J. E. Spahn, C. A. Palmiotti, D. Siegel, A. S. Ray, T. cihlar, R. Jordan, M. R. Denison and R. S. Baric, "Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses," Science Translational Medicine, vol. 9, no. 396, 2017.

【原文】

Samantha Hill

Sorry, we played an evil part in the outbreak of COVID-19

I am anonymous, I used to be an American, but I am more of an Indian. I learnt in the University of Manitoba and did some trivial work in the Fort Detrick Laboratory after graduation. My supervisor and I know almost

everything about COVID-19, and that’s why he was killed. Now I came back to India. I gather myself up and decide to tell the truth, hoping I will still be alive when all of you learn the truth.

The place I worked was quite mysterious and it is where many military biological weapons and chemical weapons are researched and developed, which is the highest level of confidentiality. Inferiors as me could only be qualified to serve the client company, but I still didn't have the clearance for all the information about any single experiment.

Gilead Sciences was my No.1 enterprise which I served most. They ever spread MERS in the Middle East so as to test the effects of a new medicine but dodge the federal restrictions. It has been an open secret that they had done experiments with GS-5734 on human being with any safety test, however, this is not what I mainly intend to say.

My supervisor was Professor Frank Plummer who used to be the best friend of Professor Ralph S. Baric. Both of them had made great and significant achievements in bioscience which must be the power entitled by Lord Shiva, but unattainable for us. Professor Plummer was more conservative while Professor Baric was a science-maniac who usually did some highly-risky experiments. I did not understand until now that he probably did not do it out of his own will but was required to do so by Gilead Sciences Inc..

Multiple experiments had been carried out after we learnt that the medicine with code of GS-5734, researched and developed by Gilead Sciences Inc., was quite effective against Ebola. This compound was probably a broadspectrum antiviral medicine and how it worked was quite special and different, thus we did experiments on a number of a single-stranded RNA viruses, including Lassa fever virus, Nipah virus, Hendra virus, coronavirus. Something special happened when we did experiments on coronavirus. It was not quite clear whether GS-5734 could effectively fight against MERS and SARS. In order to further the research, Adrian S. Ray and Richard L. Mackman from Gilead Sciences Inc. entrusted United States Army Medical Research Institute of Infectious Diseases, CDC, University of North Carolina to do researches in different fields respectively, which are the places those papers online came from. The leaders of those projects were Sina Bavari (Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys) (Warren, et al., 2016), Christina F. Spiropoulou (GS-5734 and its parent nucleoside analog inhibit Filo-, Pneumo-, and Paramyxoviruses) (Lo, et al., 2017), Ralph S. Baric (Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses) (Sheahan, et al., 2017). All the samples of SARS used in our experiments so far have come from the team led by Professor Baric since he is an expert of making SARS, publishing the paper Reverse genetics with a full-length infectious cDNA of severe acute respiratory syndrome coronavirus (Yount, et al., 2003), which means that he could have SARS virus duplicated without limits since then in 2003. He also offered fundings for Chinese Academy of Sciences for researches and made Zhengli-Li Shi the naive Snow White who helped him locate gene variation fragments for transforming SARS in Southern China.

In fact, Zhengli-Li Shi has completed the task Professor Baric gave her since the gene fragment SHC014 she discovered in China was adopted by Professor Baric to synthesize into a new type of virus in the Fort Detrick Laboratory in 2015 which is the COVI D-19 today.

That is a great experiment, and a huge progress we made in virusology and biology considering that the synthesis of RNA is unprecedent. Professor Plummer had been against this experiment, believing that it went against scientific ethics. However, Professor Baric and Gilead Sciences Inc. insisted that the synthesized virus could be taken as the reference for the original SARS in contrast experiment, and the essential subject for experiments on GS-5734.

As far as I recall, artificially breeding new type of SARS should be a research and development project for developing biological weapons entrusted by Department of National Defense (DOD). However, Gilead Sciences Inc. also had their own secret plan that they would sell GS-5734 to all over the world at a very lucrative price once the virus is leaked and spreads.

To clarify, the global widespread of COVI D-19 was not an intentional action done by Gilead Sciences Inc. or DOD but the consequence of an experimental leakage. In May, 2019, there was a leak in our experiment but we were not aware of it until villagers near labs in Maryland was infected, which was monitored by CDC in July 2019. It was too late when we found out that there were serious problems with the waste water treatment system in our lab.

Those speculative facts circulating on the Internet are not totally accurate since the rampant influenza then in South America was not totally SARSII (COVI D-19) but two kinds of viruses spreading at the same time. The outpost labs located in various states did not run tests on the coronavirus due to the Interference of CDC.

Based on the advice from Professor Baric, neither our lab nor the military and Gilead Sciences Inc. would admit the source of virus but we all tacitly referred to bats in Yunnan province in China as the source of the virus. This is possible based on the experiments and papers with Chinese scientists' involvement having proved the gene variation in nature, and the stereo type that SARS-I originated from China.

There were some controversial issues during the spread of COVID-19. In order to ensure the virus would not make irreversible damages, CDC initiated the EVENT201 drill with the assistance of CIA. Despite the

unsatisfying performance, Professor Baric believed that SARS-II would not do huge damages to Caucasians in America due to the different distribution of ACE2 in different races. This is the reason why CIA finally decided to withhold the pre-warning of the spread of the virus.

Professor Baric, Gilead Sciences Inc., BlackRock (a subcompany of Gilead Sciences for investment) and CDC are all the decision makers of the whole thing. All the members of the meeting were republicans and report to Office of American Innovation and Jared Kushner.

Then, December in 2019 was the turning point when a sailor who continued to work after being infected by SARS-II, and happened to seal the virus into the package of seafood which was transported into seafood market in Wuhan, China through the illicit market. Unexpectedly, Chinese epidemic prevention departments found out the virus, which, could probably be thanks to their prevention experience of SARS. Otherwise, the viral pneumonia could have been treated as bacterial pneumonia and named as a new type influenza without triggering enough attention.

After Chinese government found about SARS-II, my supervisor Professor Plummer was planning to share with Chinese scientific research institutions how GS-5734 could be adopted to fight against SARS-II, but he was assassinated when he was flying from Kenya to China. And I had to come back to India and hide since I got the news.

As far as I know, some colleagues knowing the truth have been killed during the last few months and some others just disappeared. All the other practitioners bowing to Professor Baric do not dare to express their doubts without the permission of him. Once their doubts was proposed, their career will be over since no publications will accept their paper any longer.

I have no idea how long I will live in this world and I feel so guilty deep down in my heart. I could not let so many lives gone even without being aware of the truth, so I make it known to the public and may Lord Shiva bless all of you. They would of course deny all of it, and even deny my identity or the existence of me. They will do whatever within their power to get me killed. So I would say goodbye right here. Farewell to all of you! I am so sorry!